SPEAKER PROFILE |
 Prof. Dr. Alexander Nesterov-Mueller Karlsruhe Institute of Technology, Institute of Microstructure Technology Germany |
AI-Based Methods for Disease Detection Using High-Density Peptide Arrays
Abstract
Our novel high-density peptide arrays provide a unique platform for the screening of interactions with antibodies, offering high spot density, adjustable spot sizes, and multiwell configurations on a single microscope slide. These arrays generate large-scale interaction data, which AI-driven analysis can decode by recognizing multiple antibody signals associated with a single disease. Moreover, neural networks improve over time by learning from growing datasets, enhancing diagnostic accuracy with each new sample.
Dr. Nesterov-Mueller earned a Dr. rer. nat. in Physics from the University of Heidelberg (2006), followed by an interdisciplinary habilitation on molecular high-density arrays at the University of Heidelberg and the German Cancer Research Center (2008). His contributions have been recognized with prestigious awards, including an ERC Starting Grant and ERC Proof-of-Principle Grants (2015, 2017). More information can be found at the link: http://www.imt.kit.edu/molecular_search_engines.php
Bio
Dr. Alexander Nesterov-Mueller, Professor at KIT, develops high-density peptide arrays for the screening of interactions with antibodies, proteins, RNA, polymers, and cells. His research advances molecular recognition, evolutionary studies, and peptide-based diagnostics.Dr. Nesterov-Mueller earned a Dr. rer. nat. in Physics from the University of Heidelberg (2006), followed by an interdisciplinary habilitation on molecular high-density arrays at the University of Heidelberg and the German Cancer Research Center (2008). His contributions have been recognized with prestigious awards, including an ERC Starting Grant and ERC Proof-of-Principle Grants (2015, 2017). More information can be found at the link: http://www.imt.kit.edu/molecular_search_engines.php